Tell your healthcare provider right away if you feel more tired than usual, have a loss of appetite, upper belly pain, dark-colored urine, or yellowing of the skin or eyes. Your doctor should do liver tests before you start, and if you have symptoms of liver problems while you are taking ZYPITAMAG. Serious liver problems have been reported rarely in patients taking statins, including pitavastatin.Tell your doctor right away if you have any unexplained muscle pain, weakness, or tenderness, particularly if accompanied by malaise or fever, or if these muscle signs or symptoms persist after discontinuing ZYPITAMAG. Muscle problems may be an early sign of rare, serious conditions.Call your healthcare provider or get help right away if you experience any symptoms of an allergic reaction, such as rash, itching, or hives.What is the most important information I should know and talk to my doctor about? You are currently taking cyclosporine or gemfibrozil.You are nursing, pregnant or may become pregnant, as it may harm the baby.You have active liver problems, including some abnormal liver test results.You have a known allergy to ZYPITAMAG or any of its ingredients.
Important Safety Information for Zypitamag® (pitavastatin) tablets Zypitamag (pitavastatin), does not interact with grapefruit juice, and therefore, you can continue to enjoy your delicious grapefruit juice. Grapefruit juice: Grapefruit juice can increase the concentration of statins in your blood, increasing the risk of side effects.Zypitamag (pitavastatin), can be taken with or without food. Some statins need to be taken with a meal, while others should be taken on an empty stomach. Taking a statin with or without food: Eating food can change how your body absorbs medications.Zypitamag (pitavastatin), tends to be more stable in your body and, as a result, can be taken at any time of the day. This is because the cholesterol-making enzyme in our body is more active at night. The time you take your statin: Some statins need to be strictly taken in the evening.As a result, it has a reduced potential to interact with certain medications you may be taking. Zypitamag (pitavastatin) is processed by your body differently than other statins. Other medications: Statins can interact with other drugs or supplements you may be taking, so be sure to disclose these to your healthcare provider.As a rule of thumb, the higher the dose of statin you take, the higher the statin concentration in your blood, leading to a greater risk of a side effect such as muscle pain.įactors affecting statin concentration in your blood: Cause of statin side effects: The risk of statin side effects increases with the statin dosage.
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